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Turn on opportunity tracking to put a dollar value on the positive replies, meetings and closed deals a sequence produces. Oneprofile adds the total to that sequence’s own analytics.
The Tracking section of a sequence's Settings tab, with Track opportunities switched on and four dollar fields for positive reply, meeting booked, meeting completed and Closed.

Opportunity tracking in a sequence's settings.

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Turn on tracking

1

Open the sequence's Settings tab

Find the Tracking section and switch on Track opportunities.
2

Set a value for each outcome

Fill in a dollar amount for a positive reply, a booked meeting, a completed meeting and a Closed. Leave any of them at zero to leave it out.

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Mark a reply as an outcome

There is no separate “mark as opportunity” button. Open a thread in the inbox and apply the Positive, Meeting booked, Meeting completed or Closed label, and it counts toward that sequence’s pipeline.

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Good to know

On that sequence’s own analytics page, as a Pipeline figure and as an Opportunities stage on the funnel chart. There is no separate pipeline dashboard.
Oneprofile counts how many threads carry each outcome label and multiplies by the dollar value you set for that outcome, then adds the four together.
Only Positive is matched by the label’s own flag. Meeting booked, Meeting completed and Closed are matched by name, so renaming or deleting one quietly drops its total to zero. Leave those three named as they came.
Yes. A thread can be labeled Meeting booked and later Closed at the same time, and both amounts count.
No. Set a value for whichever outcomes matter to you and leave the rest at zero.

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Next steps

Sequence analytics

See the pipeline total alongside every other number a sequence produces.

Inbox

Read replies and apply labels to a thread.